Publications

Publications site: under construction

1.       Filipp FV.

A gateway between omics data and systems biology

Journal of Metabolomics and Systems Biology. 2013 November 21; 1(1):1

2.       Colvin MA, Filipp FV*.

Simulations of the structural switch in PKM2 mediating the Warburg effect in cancer.

Biophysical Journal. 2014 Feb 15; 14-A-3221-BPS.

3.       Filipp FV.

Cancer metabolism meets systems biology: PKM2 is a metabolic master regulator.

Journal of Carcinogenesis. 2013 Jul 24; 12(1):1-14. [23961261]

4.       Filipp FV.

Mastering Melanoma.

International Innovation Prospectives. EU Research Media. 2013 Aug15; (22):112-122.

5.       Filipp FV.

Reversing the rewiring of cancer.

International Innovation Reports. EU Research Media. 2013 Aug15; (22):112-122.

6.       Filipp FV*, Ratnikov B, De Ingeniis J, Smith JW*, Osterman AL, Scott DA.

Glutamine-fueled mitochondrial metabolism is decoupled from glycolysis in melanoma.

Pigment Cell Melanoma Res. 2012 Nov 1. [22846158] * Corresponding author

7.       Filipp FV*, Scott DA, Ronai ZA, Osterman AL, Smith JW*.

Reverse TCA flux by reductive carboxylation through isocitrate dehydrogenases 1 and 2 is required for fatty acid synthesis in hypoxia.

Pigment Cell Melanoma Res. 2012 Feb 23. [22360810] * Corresponding author

8.       Scott DA, Richardson AD, Filipp FV, Knutzen CA, Chiang GG, Ronai ZA, Osterman AL, Smith JW.

Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect.

J Biol Chem. 2011 Dec 1. [21998308]

9.       Fang C*, Filipp FV*, Smith JW.

Unusual Binding of Ursodeoxycholic Acid to Ileal Bile Acid Binding Protein: Role in Activation of FXR alpha.

J Lipid Res. 2012 Jan 5. [22360810] * Equally contributing authors

10.    Haushalter RW, Filipp FV, Ko KS, Yu R, Opella SJ, Burkart MD.

Binding and pK(a) Modulation of a Polycyclic Substrate Analogue in a Type II Polyketide Acyl Carrier Protein.

ACS Chem Biol. 2011 May 20;6(5):413-8. [21268653]

11.    Filipp FV, Sinha N, Jairam L, Bradley J, Opella SJ.

Labeling strategies for 13C-detected aligned sample solid-state NMR of proteins

J Magn Reson. 2009 Dec;201(2):121-30. [19781966]

12.    Grage SL, Walther TH, Muhle C, Nolandt O, Klein MJ, Roth N, Mueller SD, Callow P, de Angelis A, Filipp FV, Opella S, Ulrich AS.

Pore Formation and Structure of the Twin Arginine Translocase Subunit TatA from B. subtilis.

Biophysical Journal. 2009 Feb, 96(3 S1), 194a.

13.    Neufeld C, Filipp FV, Simon B, Neuhaus A, Schueller N, David C, Kooshapur H, Madl T, Erdmann R, Schliebs W, Wilmanns M, Sattler M.

Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19.

EMBO J. 2009 Mar 18;28(6):745-54. [19197237]

14.    Filipp FV, Sattler M.

Conformational plasticity of the lipid transfer protein SCP2.

Biochemistry. 2007 Jul 10;46(27):7980-91. [17566986]

15.    Black SL, Stanley WA, Filipp FV, Bhairo M, Verma A, Wichmann O, Sattler M, Wilmanns M, Schultz C.

Probing lipid- and drug-binding domains with fluorescent dyes.

Bioorg Med Chem. 2008 Feb 1;16(3):1162-73. [18024138]

16.    Sinha N, Filipp FV, Jairam L, Park SH, Bradley J, Opella SJ.

Tailoring 13C labeling for solid-state NMR experiments on aligned samples of proteins.

Magnetic Resonance in Chemistry. 2007 Dec; 45(S1): 107-115. [18157808]

17.    Filipp FV.

From bench to bedside. Alain Fischer, immunologist and gene therapist at Necker Hospital Paris, France.

EMBO Rep. 2007 May;8(5):429-32. [17471256]

18.    Filipp FV.

Is science killing sport? Gene therapy and its possible abuse in doping.

EMBO Rep. 2007 May;8(5):433-5. [17471256]

19.    Stanley WA, Filipp FV,Kursula P,Erdmann R,Schliebs W, Sattler M, Wilmanns M.

Recognition of a functional peroxisome type 1 target by the dynamic import receptor Pex5p.

Mol Cell. 2006 Dec; 24(5):1000-10. [17157249]

20.    Mapelli M, Filipp FV, Rancati G, Massimiliano L, Nezi L, Stier G, Hagan RS, Confalonieri S, Piatti S, Sattler M and Musacchio A.

Determinants of conformational dimerization of Mad2 and its inhibition by p31comet.

EMBO J, 2006 Mar 22;25(6):1273-84. [16525508]

21.    Stanley WA, Filipp FV, Kursula P, Svergun DI, Sattler M, Wilmanns M.

Receptor recognition by the flexible peroxisomal targeting signal type 1 of sterol carrier protein 2.

Acta Cryst. March 2004: A60, S175. [17157249]

22.    Peng C, Unger SW, Filipp FV, Michael Sattler M, Szalma S.

Automated evaluation of chemical shift perturbation spectra: New approaches to quantitative analysis of receptor-ligand interaction NMR spectra.

J Biomol NMR. 2004 Aug;29(4):491-504. [15243180]

23.    Filipp FV*, Douangamath A*, Klein ATJ, Barnett P, Zou P, Voorn-Brouwer T, Vega MC, Mayans OM, Sattler M#, Distel B, Wilmanns M#. Topography for independent binding of a-helical and PPII-helical ligands to a peroxisomal SH3 domain.

Mol Cell. 2002 Nov;10(5):1007-17. [12453410] * Equally contributing authors

24.    Douangamath A, Filipp FV, Mayans OM, Vega MC, Barnett P, Sattler M, Distel B, Wilmanns M.

Structural Studies of a dual ligand binding SH3 domain in Pex13p.

Acta Cryst. 2002 Aug: A58, C286. [12453410]